palytoxin

(redirected from PTX)
Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.

palytoxin

(păl′ə-tŏk′sĭn)
n.
A powerful toxin that occurs in corals of the genus Palythoa of the South Pacific and disrupts the flow of ions across cell membranes. It is rapidly fatal to humans in very small doses and is one of the most complex naturally occurring substances.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

palytoxin

(păl″ĭ-tŏk′sĭn) [Fr. Paly(thoa), the genus name of a coral + ″],

PTX

A potent toxin produced by microscopic marine algae that grow on coral. It destroys blood cells, alters cardiac conduction, and damages nerves. Intoxication with PTX can result in bleeding, weakness, blood vessel constriction, ventricular fibrillation, and death.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
PTX released from the polymer membrane was diluted in phosphate-buffered saline (PBS; pH 7.4) with 0.9% sodium chloride solution and 0.1% Tween 80 (w/v).
(Cleveland, OH, USA) introduced the micropower impulse radar (MIR) based PneumoScan (CE-certificate 561036) to detect or exclude PTX within seconds.
Lastly, the PTX was loaded by adding 0.01 g [Fe.sub.3][O.sub.4]/RGO to PBS buffer solution containing PTX (1 mg/mL, 30 mL) at 25[degrees]C for 16 h in dark.
PGE, OMZ, SCF, and PTX showed little or no change in their protein content compared with control EtOH group.
The conditioned media from DB-ASCs, both primed with PTX (CM/PTX) or not (CM CTRL), were tested on the standard laboratory tumour cell line CFPAC-1 (Figure 5).
The mean duration of hospitalisation was 49.46+-13.52 days for the PG group and 44.21+-11.1 days for the PTX group neonates (p>0.05).
PTX surgical operation was standardized in the five hospitals through a training program and a unified postoperative treatment process was implemented and managed by the China-Japan Friendship Hospital.
Due mainly to its capacity to inhibit production of TGF-[beta]1, FGF, and PDGF [77-80], PTX can reduce collagen deposition, as well as having strong inhibitory effects on fibroblast proliferation, ECM synthesis, and myofibroblastic differentiation.
Particularly, cell proliferation kit I (MTT) assay was used to determine the ability of PTX-Lips to minimize the toxicity to HeLa cells of PTX. This study is expected to improve the stability of Lips which was synthesized by eco-friendly SL for PTX delivery in cancer therapy.
To reveal whether intranasal Ptx pretreatment ameliorated the mesodopaminergic activity in SE rats, the markers of mesodopaminergic system were analyzed.
In the current study, BA was chosen as a preoxidant to synergize with Ptx. The synergistic antitumor effect of BA and Ptx was evaluated in both in vitro and in vivo tumor models.
Gathering the current knowledge together, herein it is hypothesized that PTX can be used as a treatment regime for HT with the goal of remission of the disease but not palliation of disease symptoms.