placental site trophoblastic tumor

(redirected from PSTT)
Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

pla·cen·tal site troph·o·blas·tic tu·mor

a tumor usually arising in the uterus of parous women during reproductive years. Histologically, the tumor consists of a predominance of intermediate trophoblastic cells with fibrinoid material and vascular invasion.
Farlex Partner Medical Dictionary © Farlex 2012

placental site trophoblastic tumor

Gynecologic pathology
A rare uterine neoplasm of gestational tissue of reproductive age ♀, presenting as a 'missed' abortion, which ranges from microscopic to massive and from 'timid' to highly aggressive that actively secretes human placental lactogen Prognosis 10% mortality
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

placental site trophoblastic tumor

Abbreviation: PSTT
A rare form of gestational trophoblastic disease simulating carcinoma and arising at the attachment of the placenta to the uterine wall.
See also: tumor
Medical Dictionary, © 2009 Farlex and Partners
Mentioned in ?
References in periodicals archive ?
Epithelioid leiomyoma or leiomyosarcoma may simulate PSTT because of their shared epithelioid cytology.
(40) Compared with gestational choriocarcinoma and PSTT, 50% of ETTs arise from the uterine cervix or lower uterine segment.
Atypical PSN has been proposed as an immediate precursor lesion to gestational trophoblastic tumors (ETT and PSTT).
Gestational Trophoblastic Tumors: A Timely Review of Diagnostic Pathology
PSTT grows very slowly and metastasize occurs after several years.
* Cesarean scar placental site trophoblastic tumor (PSTT) and cervicoisthmic choriocarcinoma are rare conditions.
* A rare case of PSTT from previous cesarean scar is reported.
Placenta Site Trophoblastic Tumor and Choriocarcinoma from Previous Cesarean Section Scar: Case Reports
PSTT may be hypovascular or hypervascular, with the former form being not associated with prominent vascularity on Doppler ultrasound [2,12].
It is sometimes used as a problem-solving tool to assess the depth of myometrial invasion and extrauterine disease spread in equivocal and complicated cases, suspected PSTT, and recurrent GTN [1, 2].
However, the hypovascular form of PSTT has been demonstrated to be hyperintense to myometrium on both T1- and T2-weighted images with absence of prominent vascularity or flow voids and poor enhancement on postcontrast images [2].
Gestational trophoblastic disease: a multimodality imaging approach with impact on diagnosis and management
ADAMTS-1 showed weak positivity in early complete moles, intermediate positivity in invasive moles, and strong positivity in PSTTs and choriocarcinomas.
Expression of ADAMTS subtypes in PSTTs. A and B, ADAMTS-1 and ADAMTS-4 immunohistochemical staining, respectively, shows strong positivity in PSTTs.
Differential Expression Patterns of a Disintegrin and Metalloproteinase With Thrombospondin Motifs (ADAMTS) -1, -4, -5, and -14 in Human Placenta and Gestational Trophoblastic Diseases

Medical browser ?
Full browser ?