placental site trophoblastic tumor

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pla·cen·tal site troph·o·blas·tic tu·mor

a tumor usually arising in the uterus of parous women during reproductive years. Histologically, the tumor consists of a predominance of intermediate trophoblastic cells with fibrinoid material and vascular invasion.
Farlex Partner Medical Dictionary © Farlex 2012

placental site trophoblastic tumor

Gynecologic pathology
A rare uterine neoplasm of gestational tissue of reproductive age ♀, presenting as a 'missed' abortion, which ranges from microscopic to massive and from 'timid' to highly aggressive that actively secretes human placental lactogen Prognosis 10% mortality
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

placental site trophoblastic tumor

Abbreviation: PSTT
A rare form of gestational trophoblastic disease simulating carcinoma and arising at the attachment of the placenta to the uterine wall.
See also: tumor
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Epithelioid leiomyoma or leiomyosarcoma may simulate PSTT because of their shared epithelioid cytology.
(40) Compared with gestational choriocarcinoma and PSTT, 50% of ETTs arise from the uterine cervix or lower uterine segment.
Atypical PSN has been proposed as an immediate precursor lesion to gestational trophoblastic tumors (ETT and PSTT).
PSTT grows very slowly and metastasize occurs after several years.
* Cesarean scar placental site trophoblastic tumor (PSTT) and cervicoisthmic choriocarcinoma are rare conditions.
* A rare case of PSTT from previous cesarean scar is reported.
PSTT may be hypovascular or hypervascular, with the former form being not associated with prominent vascularity on Doppler ultrasound [2,12].
It is sometimes used as a problem-solving tool to assess the depth of myometrial invasion and extrauterine disease spread in equivocal and complicated cases, suspected PSTT, and recurrent GTN [1, 2].
However, the hypovascular form of PSTT has been demonstrated to be hyperintense to myometrium on both T1- and T2-weighted images with absence of prominent vascularity or flow voids and poor enhancement on postcontrast images [2].
ADAMTS-1 showed weak positivity in early complete moles, intermediate positivity in invasive moles, and strong positivity in PSTTs and choriocarcinomas.
Expression of ADAMTS subtypes in PSTTs. A and B, ADAMTS-1 and ADAMTS-4 immunohistochemical staining, respectively, shows strong positivity in PSTTs.