TAP1

(redirected from PSF1)
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TAP1

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment.

Molecular pathology
TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease.
References in periodicals archive ?
Week Three: QPO1 Winner v PSF1 Winner* (Qualifying Semi Final 1, QSF1), QPO2 Winner v PSF2 Winner* (Qualifying Semi Final 2, QSF2).
It comprises 14 Paragon buy-to-let (BTL) deals and one non-conforming RMBS transaction, Paragon Secured Finance (PSF1), which is fully backed by second-charge loans.
As of January 2016, PSF1's late arrears were reported at 10.4%, 1.2pp above the Fitch UK Non-Conforming Index.