TAP2

(redirected from PSF-2)

TAP2

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance and antigen presentation. TAP2 forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum.

Molecular pathology
TAP2 mutations have been tentatively linked to ankylosing spondylitis, type-1 diabetes and coeliac disease.
References in periodicals archive ?
In order to study the effect of solvent on morphology and performance of pure PSf membrane, three different membranes (PSf-1, PSf-2, and PSf 3) were fabricated.
PSf-1, PSf-2, and PSf-3 which were prepared by different solvents (NMP, THF, and NMP/THF respectively) and same external nonsolvent (IPA-50%) had different morphologies and gas separation properties.
Solvent (wt%) Internal Membrane nonsolvent (PSF 22 wt%) NMP THF NMP/THF (wt%) BuOH PSf-1 78 -- -- -- PSf-2 -- 78 -- -- PSf-3 -- -- 78 -- PSf-4 -- -- 76 2 PSf-5 -- -- 72 6 PSf-6 -- -- 68 10 TABLE 2.