TAP1

(redirected from PSF-1)

TAP1

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment.

Molecular pathology
TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease.
References in periodicals archive ?
As lower solubility parameter difference between solvent and nonsolvent results in delayed phase demixing, PSf-1 which was prepared by pure IPA as external nonsolvent had a less porous structure and high C[O.sub.2]/C[H.sub.4] selectivity of 36.40 in 1 bar feed pressure.
In order to study the effect of solvent on morphology and performance of pure PSf membrane, three different membranes (PSf-1, PSf-2, and PSf 3) were fabricated.
A comparison of membrane porosity for prepared PSf-1 membranes with various nonsolvents is presented in Table 3.
Membranes with various compositions were labeled from PSf-1 to PSf-6 (Table 1).