DLG2

(redirected from PSD93)

DLG2

A gene on chromosome 14q14.1 that encodes a member of the membrane-associated guanylate kinase (MAGUK) family, which forms a heterodimer with related family members, interacting at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signalling proteins. DLG2 is also the retired HUGO symbol for what is now designated MPP2, see there.
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Shank3 and other scaffolding proteins, PSD95 and PSD93, undergo proline-directed phosphorylation and share a similar phosphorylation motif [48].
On the other hand, in [Shank2.sup.PC] mice, only GluD2 (GluRD2) and PSD93 were significantly reduced [165].