SF3A1(redirected from PRPF21)
SF3A1A gene on chromosome 22q12.2 that encodes subunit 1 of the splicing factor SF3A, which is required for “A” complex assembly by the stable binding of U2 snRNP to the branchpoint sequence in pre-mRNA. It may anchor U2 snRNP to pre-mRNA and be involved in assembling the “E” complex.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.