PROKR2

PROKR2

A gene on chromosome 20p12.3 that encodes the G protein-coupled receptor for prokineticin 2, one of a family of proteins that promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. PROKR2 activation mobilises calcium, stimulates phosphoinositide turnover and activates p44/p42 mitogen-activated protein kinase.
References in periodicals archive ?
Hardelin JP, Dode C, 2008 The complex genetics of Kallmann syndrome: K AL1, FGFR1, FGF8, PROKR2, PROK2, et al.
Kallmann syndrome caused by mutations in the PROK2 and PROKR2 genes: pathophysiology and genotype-phenotype correlations.
Increased production of this protein - known as PROKR2 - makes a pregnancy more likely to implant in the Fallopian tube.