2011) patients Inferior vena Literature cava filters (PREPIC
Study Group for the prevention of 2005; Sarosiek, pulmonary embolism Crowther, and Sloan 2013) Pulmonary Artery Literature Catheterization in the (Rajaram et al.
In the PREPIC (Prevention du Risque d'Embolie Pulmonaire par Interruption Cave) randomized trial evaluating the long-term outcomes of patients with proximal DVT, investigators concluded that the 8-year incidence of recurrent DVT was significantly higher in the group of 200 patients implanted with permanent IVC filters than in the 200 patients who did not receive filters .
The PREPIC trial and the CFD analyses performed by Singer et al.
Similar results have been reported from the PREPIC
trial, a prospective, randomized, controlled study of 400 patients, which showed that at 8 years, IVCF reduced the risk of pulmonary embolism but increased DVT and had no effect on survival (12).
(5) The PREPIC study randomised 400 patients with confirmed proximal deep vein thrombosis to either anticoagulation alone or IVC filter placement in combination with anticoagulation.
Summary of PREPIC findings with filter use Time PE Recurrent DVT Survival 12 days [down arrow] 2 years = [up arrow] = 8 years [down arrow] [up arrow] = This study provides valuable information that the placement of filters is of little value in patients who have no contraindication to the use of anticoagulation.
He was an investigator in the PREPIC
(Prevention du Risque d'Embolie Pulmonaire par Interruption Cave) trial, which this summer reported filters reduced risk of pulmonary embolism but increased risk of deep venous thrombosis (Circulation 2005;112:416-22).