AURKA

(redirected from PPP1R47)

AURKA

A gene on chromosome 20q13 that encodes Aurora kinase A, which is involved in regulating many early mitotic events such as entry into mitosis. Aurora A levels rise during the G2 phase and peak early in mitosis. It is highly expressed in the testes, as well as in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
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The Aurora-A is encoded by the AURKA gene (also known as AIK, Aurora/IPL1-like kinase; ARK1, Aurora related kinase 1; AURA, AURORA2; BTAK, breast tumoramplified kinase; PPP1R47, protein phosphatase 1 regulatory subunit 47; STK15, serine/threonine-protein kinase 15; STK6, serine/threonine kinase 6), located at 20q13.2 and consisting of 11 exons (Gene ID: 6790).