Effects of the PPARG
P12A and C161T gene variants on serum lipids in coronary heart disease patients with and without Type 2 diabetes.
1,25-Dihydroxy-vitamin D3 (active form of vitamin D) inhibits preadipocyte differentiation  and suppresses adipogenic PPARG
gene expression in 3T3 L1 cells .
After the treatment with A combination of FA and gemcitabine, a significant increase was observed in the expressions of CASP3, CASP7, CASP8, FAS, CYCS, TNF and PPARG
genes compared with the control group (p<0.05).
also observed downregulation of PPARG
. It means that the PPAR[gamma]-seipin relation is not only restricted to adipogenesis or adipose tissue .
Three differentially expressed genes from E2- or ER agonist-treated cells identified by RNA-Seq, peroxisome proliferator-activated receptor gamma (PPARG
, GeneID 5468), suppressor of cytokine signaling 3 (SOCS3, GeneID 9021), and interleukin 6 receptor (IL6R, GeneID 3570) were validated using quantitative PCR.
All patients with CGL and FPLD underwent molecular genetic studies of the genes AGPAT2, BSCL2, CAV1, PTRF, LMNA, LMNB2, PPARG
, PLIN1, AKT2, and CIDEC that confirmed mutations in AGPAT2, BSCL2, PTRF, LMNA, PPARG
loci in most patients.
GW9662 (10[micro]mol/L), a selective PPARg
antagonist, could abolish the effects of curcumin.
Variants in PPARG
, KCNJ11, TCF7L2, FTO and HHEX genes in South African subjects of Zulu descent with type 2 diabetes.
Researchers from University of California - Davis Health System identified the host receptor peroxisome proliferator receptor gamma (PPARg
) as the regulator responsible for maintaining this cycle of protection.
Adipogenic genes were also overexpressed; a 1.5- to 2.4-fold increase was seen in PPARG
, for example.
Telmisartan, an angiotensin type 1 (ATI) receptor blocker, reportedly has beneficial effects on glycemic control more than other ATI receptor blockers and this unique feature of telmisartan can be due to its peroxisome proliferator activated receptors (PPARg
) agonistic activity3.
ThyroSeq v2 panel Gene mutations Gene fusions Gene expression (RNA) (DNA) (RNA) BRAF RET RET PGK1 Pan-cell NRAS TSHR PPARG
KRT7 HRAS AKT1 NTRK1 TG Thyroid cell KRAS TP53 NTRK3 TTF1 PIK3CA GNAS BRAF NIS PTEN CTNNB1 ALK Calcitonin MTC TERT EIF1AX PTH Parathyroid KRT20 Metastatic