POU2AF1
(redirected from POU domain class-2-associating factor 1)POU2AF1
A gene on chromosome 11q23.1 that encodes a transcription coactivator that recognises the POU domains of OCT1 and OCT2, boosting OCT1 mediated promoter activity and, to a lesser extent, that of OCT2. POU2AF1 is essential for B-cell response to antigens and required for germinal centre formation.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.