GIF

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macrophage migration inhibitory factor

A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration.

Gene
MMIF is encoded by MIF on chromosome 22q11.23.

Activities
Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.
 
Mechanism
Increases intracellular cAMP, polymerises microtubules, stops macrophage progression.

GIF,

References in periodicals archive ?
The PNG, he explained, has so much potential in agriculture.
Given the growing role of resources in the PNG economy, combined with still endemic poverty and weak governance and corruption, it would be natural to expect PNG to demonstrate some of the characteristics of the 'resource curse'.
There is no disagreement about one thing: time spent in PNG during this period was formative to many prominent Australians, leaving an indelible mark that continues to inform both professional and personal outlooks.
PNG women's groups say they hope the forum will become an annual event, and the embassy hopes that the women of PNG will take up the torch to make this a reality.
It is hoped that either site or possibly both will contain the resources to support an expansion of capacity at PNG LNG.
He however stressed that those arriving in boats and who will be assessed in PNG, will not be included in this intake.
The PNG MLST sequences were compared with previously reported sequences by using the same 9 loci outlined in previous studies (5-7).
England's young team are more than skilful enough to beat PNG but they will have to match their tenacity and pride in their jersey.
The broad-based support the Project is receiving from the Government and the people of PNG is highly encouraging.
The Papua New Guinea Nurses' Association told Radio Australia that a study into their workloads by the Australian Nurses' Federation in 2006 recommended salary reclassifications and pay rises for their PNG counterparts.
The PNG Yearbook series is an established annual publication that attempts to document social and economic progress in PNG, as well as something of the flavour of life in PNG.