APP

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APP

abbr.
amyloid precursor protein

APP

A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

APP

Amyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
References in periodicals archive ?
Al realizar el test de Student para comparacion de medias de datos apareados encontramos diferencias estadisticamente significativas (<0,05), entre QA PR y QA PR2, entre QA PN y QA PN2 y entre QAm1 y QAm2.
Thus for samples PN2.5-3 and PN4-3 which have the lowest storage modulus plateau the PP/PP-g-MA matrix predominantly controls the viscoelastic behavior at high frequencies.
* Besides sweeping the shipping lanes for mines to keep other vessels safe, PN2 (SW) Dale Estridge and SK2 Charles Wade stand mine watches around the clock to keep their own ship safe.
Las tiras, de los diferentes bistes obtenidos de cada pieza de pulpa negra (PN), se introdujeron en bolsas plasticas, identificadas por la pieza del cual se derivaron (PN1, PN2....
1900-1920, caribou occurred along most of the coast of Hall Peninsula and on islands in Frobisher Bay (HK, LN2, PN2, OQ, Fig.
PN2: P[L([T.sub.1],[theta]) [less than or equal to] L([T.sub.2],[theta])] > 1/2
Axillary lymph nodes were examined for the total number of lymph nodes removed, number of positive lymph nodes (pN), and lymph node ratio (LNR.) The number of positive lymph nodes on histopathological examination was stratified according to the staging system of the American Joint Committee on Cancer and The Union for International Cancer Control (AJCC/UICC) into pNl (1-3 positive lymph nodes), pN2 (4-9 positive lymph nodes), and pN3 (>10 positive lymph nodes) (14, 15).
The degree of lymphatic invasion, venous invasion, perineural invasion, pancreatic invasion, and duodenal invasion was classified in detail as follows: ly0, v0, pn0, panc0, and du0 = no evidence of invasion; ly1, v1, pn1, panc1, and du1 = mild invasion; ly2, v2, pn2, panc2, and du2 = moderate invasion; and ly3, v3, pn3, panc3, and du3 = severe invasion, respectively [2].