Bai et al., "Plant homeo domain finger protein 8 regulates mesodermal and cardiac differentiation of embryonic stem cells through mediating the histone demethylation of pmaip1
," Stem Cells, vol.
The expression of intracellular IL-33 and IL-33-regulated genes such as OAS1, GATA3, and PMAIP1
was increased in relapsing remitting MS patients (RRMS) .
Su, "Parthenolide induces apoptosis via TNFRSF10B and PMAIP1
pathways in human lung cancer cells," Journal of Experimental and Clinical Cancer Research, vol.
HCC with recurrence exhibited enrichment of upregulated genes mapping to signaling or disease pathways associated with cell cycle regulators (CDKN2B, E2F2, E2F5, GNL3, HDAC2, MDM2, MYC, and PA2G4), including the genes that encode the proteins that control molecular mechanisms of cancer (FANCD2, FZD3, PLCB1, and PMAIP1
Two in particu1ar, PMAIP1
, a tumor suppression gene on chromosome 18, and PTPN1, an oncogene on chromosome 20, proved pivotal in identifying patients with head and neck cancer.