Protein and RNA Expressions of TRIM29, DSP, and PKP1 Are Correlated and Their Reductions Are Associated With Poor Prognosis
Examples of the correlation between RNA and protein expression for 3 peptides are shown in Figure 3: DSP, the tripartite motif-containing protein 29 (Trim29), and PKP1. Correlation of protein and RNA expression was not skewed by outliers and is evenly distributed across the range of expression.
Reduced Cell-Cell Adhesion Through Down-Regulated DSP, PKP1, and KRTs Contributes to Poor Prognosis
(36) In the current study, lower levels of PKP1 protein and RNA were associated with DM and diseasespecific survival.
Overall, down-regulation of DSP, PKP1, and several KRTs has been observed to associate with DM and DSD in this study.