RIPK4

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Also found in: Acronyms.

RIPK4

A gene on chromosome 21q22.3 that encodes a serine/threonine/ tyrosine kinase, which is a transcriptional target of TP63. RIPK4 plays a role in NF-kappaB activation, and it interacts with PRKCB, TRAF1, TRAF2, TRAF3, TRAF5, BIRC2/c-IAP1, BIRC3/c-IAP2 and XIAP/BIRC4.

Molecular pathology
RIPK4 mutations cause popliteal pterygium syndrome, lethal type.
References in periodicals archive ?
A police officer succumbed to his wounds on Thursday after he was injured during an operation against the PKK in Silvan.
PKK shelters and gun positions were destroyed in the Metina and Zap areas of northern Iraq in Sunday's air raids, a military statement said.
Before March 2014, the YPG tried to recruit mostly Syrian Kurds to avoid the image of being too closely linked to the PKK, still listed as a terrorist organization by the United States, the EU, and Turkey.
Meanwhile, one police officer was killed and another injured in the Southeastern Turkish province of Diyarbakir in another attack by the PKK on Sunday.
Some Kurdish media outlets reported that as many as two PKK guerillas may have been killed in the airstrikes in Zargali, although the PKK has not confirmed such reports.
These included the abolition of a terrorist law used to jail thousands of alleged PKK affiliates and allowing Kurdish schoolchildren to be taught in their own language.
It is the first attack by the Turkish army against PKK targets following the call by the PKK leader for his followers to stop fighting Turkish forces and withdraw from Turkish territories.
In accordance with its Marxist-Leninist ideology, to cite Lenin himself, the intelligentsia for PKK "is not "the brain of the nation", it is the" feces of the nation.
and also expressed irritation at Damascus and Tehran's hints that they will use the PKK issue to bargain over Ankara's position on the crisis in Syria, the pan-Arab daily newspaper AL HAYAT reported on Tuesday.
The PKK confirmed that they had staged a deadly attack on Turkish troops.
Turkey has been fighting the PKK since 1984, when it took up arms to carve out a homeland in southeastern Turkey.
Turkish jets bombed PKK targets shortly before midnight on May 1 and continued into May 2.