PKD


Also found in: Dictionary, Thesaurus, Acronyms, Wikipedia.

PKD

abbreviation for polycystic kidney disease.

kidney disease, polycystic

,

PKD

An inherited renal disorder transmitted as an autosomal recessive trait in infants and as an autosomal dominant trait in adults. PKD was previously termed adult polycystic kidney disease. It is characterized by cyst formation in ductal organs, particularly the kidney and liver, and by gastrointestinal and cardiovascular abnormalities. Included are colonic diverticula, cardiac valvular abnormalities, and intracranial and aortic aneurysms. Symptoms include hypertension, acute and chronic pain, and urinary tract infections. It is one of the most common hereditary disorders, occurring in about 1 in 400 to 1 in 1000 people. An estimated 500,000 persons have the disease in the U.S. It accounts for 10% of cases of end-stage renal disease. Treatment includes medical therapy for renal failure with eventual renal dialysis and renal transplantation.

polycystic kidney disease

,

PKD

Any of several hereditary disorders in which cysts form in the kidneys and other organs, eventually destroying kidney tissue and function. The autosomal recessive form usually appears in early childhood; the autosomal dominant form usually develops later in life. Definitive treatments are dialysis and kidney transplant. Because cerebral aneurysms are commonly found in adults with PKD, patients with this disorder are often screened with computed tomography or magnetic resonance imaging studies of the brain.
References in periodicals archive ?
country in the Middle East that implemented a National PKD solution.
com/lucy-moore2 For more information about PKD visit www.
Gertrude Robert, 80, is the 2011 coordinator of the Worcester Walk for PKD, founded by the family in 2006 to raise money and awareness.
Meanwhile, several other drugs, including rapamycin, octreotide, and tolvaptan, that succeeded in animal tests for PKD are now being tested in people.
More information about PKD can be found online at www.
We hope to meet with AVI very soon to discuss plans for further development of this drug in PKD patients.
Autosomal dominant PKD is the most common inherited form.
PKD causes fluid-filled cysts to form in the kidneys, disrupting their ability to remove harmful toxins from the body.
When PKD causes kidneys to fail--which usually happens only after many years--the patient requires dialysis or kidney transplantation.
This public presentation is part of an ongoing series of free 2-hour informational support meetings hosted by the Hamilton Chapter of the PKD Foundation of Canada.
In PKD, large cysts form within the kidney and disrupt the organ's function.