AKT1

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AKT1

A gene on chromosome 14q32.32|14q32.32 that encodes protein kinase B (PKB), a serine-threonine protein kinase that is rapidly and specifically activated by platelet-derived growth factor through phosphatidylinositol 3-kinase. PKB plays a key role in regulating cell survival, insulin signalling, angiogenesis, tumour formation and growth factor-induced neuronal survival. Activated AKT1 phosphorylates and inactivates components of the apoptotic machinery.
References in periodicals archive ?
Mohammad Kefayet Ullah, Deputy Managing Director of PKB, said, "There will be a number of investment and rehabilitation packages for returning expatriates who want to start business hassle-free.
Dr Al Ubaydli said hospitals and medical centres that have affiliated with the PKB give their patients an online ability to securely access their medical documents, history and test results, have online consultations with their doctors and receive prescriptions.
Anche il secondo studio, realizzato da Christodoulides (24), si e prefisso di indagare la validita del PKB nella diagnosi di ernia discale lombare.
With the addition of new DFARS approved American vendors, PKB has streamlined the factory production to ensure reliable on-time delivery performance.
No significant decrease in PKB and GSK3[beta] phosphorylation on induction with DEX was observed at all the three time points (12, 24 and 48h) compared to the uninduced control (Fig.
Likewise, cardholders who opt to take their vehicle to Bravo PKB Meridian showrooms can expect a 5% discount on tire fittings and storage, and paintless dent removal.
He also secured the support of the PKB and others from the PAN and PPP will probably come over.
Support for the Megawati-Hasyim Muzadi pair is expected to be stronger especially with the disqualification of PKB presidential candidate Abdurahman Wahid, who is more popular among the N.
The free-market policies of the PKB, PAN and PDI Struggle's senior economists have not been perfectly reconciled with the parties' popular support bases.
The new lathe will enable PKB to improve on its uniquely short leadtimes.
He said his party is open to the possibility of forming a coalition with other parties and has intensively communicated with PKB, Golkar, PKS and the Crescent Star Party (PBB) led by Justice and Human Rights Minister Yusril Ihza Mahendra.
PKB was evaluated throughout every phase of the ball bearing manufacturing process, including procurement, production, and testing to accounting, logistics, information systems and human resources.