AKT1

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AKT1

A gene on chromosome 14q32.32|14q32.32 that encodes protein kinase B (PKB), a serine-threonine protein kinase that is rapidly and specifically activated by platelet-derived growth factor through phosphatidylinositol 3-kinase. PKB plays a key role in regulating cell survival, insulin signalling, angiogenesis, tumour formation and growth factor-induced neuronal survival. Activated AKT1 phosphorylates and inactivates components of the apoptotic machinery.
References in periodicals archive ?
The framework adds to work already being done by PKB at a national level with NHS Wales and young adults' diabetes services across all local health boards in Wales, as well as the 1,000 Lives Project with the Ear Nose and Throat department in Cardiff and Vale University Health Board.
PKB understands the unique challenges presented by aerospace and guidance applications.
This network consists of 15 GNSS stations, including 6 stations stabilised inside the PKB, 5 stations within the MN and 4 stations within the PF (see Fig.
The effects of rosiglitazone (insulin sensitizing positive control) on the insulin signaling proteins such as IR[beta], PTPIB, PI3K, PKB, GSK3[beta] and GLUT4 in the insulin sensitive and dexamethsone induced insulin resistant model of 3T3L1 adipocytes were assessed using ELISA experiments.
Mohammad Kefayet Ullah, Deputy Managing Director of PKB, said, "There will be a number of investment and rehabilitation packages for returning expatriates who want to start business hassle-free.
Dr Al Ubaydli said hospitals and medical centres that have affiliated with the PKB give their patients an online ability to securely access their medical documents, history and test results, have online consultations with their doctors and receive prescriptions.
Parties such as PKS, PPP, PAN and PKB are considered as the most Islamic, while parties such as Golkar, PDI-P, PD and Gerindra are perceived as the most "Pancasila based" or nationalist or secular.
La prima, di Postacchini et al (23), ha indagato la validita del PKB (denominato "Knee Flexion Test") nella diagnosi di ernia discale.
The PKS would be more sympathetic to Hamas than Gus Dur, the previous Indonesian president and PKB leader, who observed Gaza and Hamas from an observation post through an Israeli telescope.
PKB joins a variety of SAI Global newsfeeds, alerts and databases in such areas as ethics, compliance and culture, and anti-laundering money.
Designed for on-board distributed power architectures in wireless base stations, inter-networking and other telecom applications, the PKB series modules provide up to 20 A at 3.
6m, its X axis movement of up to 6m and Z axis movement of up to 1200mm, the PKB is capable of machining substantia patterns or carbon fibre components at high speed.