Given our experience with CE-MRA, which was started three years before publication of the PIOPED III data, (16) we have taken a different approach by focusing on the test effectiveness of CE-MRA for PE.
Diagnostic pathways in acute pulmonary embolism: Recommendations of the PIOPED II investigators.
Weg et al., "Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II--investigators," Radiology, vol.
Goodman, "Acute pulmonary embolism: sensitivity and specificity of ventilation-perfusion scintigraphy in PIOPED II study," Radiology, vol.
Stein PD, Chenevert TL, Fowler SE, Goodman LR, Gottschalk A, Hales CA, et al for the PIOPED III (Prospective Investigation of Pulmonary Embolism Diagnosis III) Investigators.
Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED).
PIOPED and Prospective Investigation of Pulmonary Embolism Diagnosis II (PIOPED II) were designed to evaluate the effectiveness of certain diagnostic techniques in contributing to a true positive PE test result.
A significant finding of PIOPED was that a normal lung V/Q study excluded the diagnosis of clinically significant PE.
CT venography and compression sonography are diagnostically equivalent: Data from PIOPED
Studies that compared single-detector spiral CT pulmonary angiography with V/Q scanning showed that CT was a more accurate examination with higher specificity, particularly in those patients with underlying cardiopulmonary disease in whom the vast majority (90% in the PIOPED
1 study) have indeterminate V/Q scan results.