PIGX

PIGX

A gene on chromosome 3q29 that encodes a protein thought to stabilise the mannosyltransferase PIGM. It is an essential component of glycosylphosphatidylinositol (GPI)-mannosyltransferase 1, and transfers mannose residues in the GPI-anchor precursors during GPI-anchor biosynthesis.
References in periodicals archive ?
The blue coexpression network consisted of 16 variably expressed genes (see Supplemental Table 1 for GO) and included phosphatidylinositol glycan anchor biosynthesis class X (PIGX) as a potential hub gene based on a connection weight of 0.4 (Figure 4, A).
One network included hub gene PIGX, a key player during glycosylphosphatidylinositol anchor synthesis.
A connection weight cutoff of 0.4 was used within the VisANT software (55) to visualize the genes with the most connections and identify the hub gene, phosphatidylinositol glycan anchor biosynthesis class X (PIGX).