PIGW

PIGW

A gene on chromosome 17q12 that encodes a probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol. PIGW is involved in glycolipid and glycosylphosphatidylinositol-anchor biosynthesis.
References in periodicals archive ?
The top five genes with a high absolute value of coefficient factor, namely, (PIGQ), 284098 (PIGW), 2822 (GPLD1), 5281 (PIGF), and 5279 (PIGC), are selected to represent the genes for this canonical variable (Figure 4(b), Table 1).
To date, mutations in six genes (PIGV, PIGY, PIGO, PGAP2, PIGW, and PGAP3) have been shown to cause hyperphosphatasia with mental retardation syndrome (HPMRS) in an autosomal recessive mode of inheritance (no autosomal dominant mutations have been reported thus far).
PIGW gene), the structure of the PI moiety changes in GlcN-(acyl)PI from the diacyl form to a mixture of 1-alkyl-2-acyl as the major form and the diacyl form as a minor form.