SERPINB10

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SERPINB10

A gene on chromosome 18q21.3 that encodes a member of the serine protease inhibitor (serpin) family, which regulate a wide range of intracellular and extracellular processes, such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumour suppression, apoptosis and cell migration. SERPINB10 may play a role in regulating protease activities during haematopoiesis and apoptosis induced by TNF, and it may regulate proteases in the cytoplasm and nucleus.
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References in periodicals archive ?
In this study, we analyzed the lung volume ([cm.sup.3]), emphysema volume ([cm.sup.3]) and index (emphysema/lung volumes, in %), lung mean density (HU), relative bronchial wall thickness (to bronchus diameter, in %) for 3rd to 8th bronchi generation (excluding trachea and main bronchi), Pi10 (normalized measurement of wall thickness for a standardized 10 mm diameter bronchus), and the number of measured bronchi (which correlates with bronchodilation and presence of bronchiectasis) (21).
Using Cirrus Lung 13.05 software (Diagnostic Image Analysis Group, Netherlands), the average wall thickness and percentage wall area of the 4th- and 5th-generation bronchi were measured, and the aggregated airway diameter for individual patients was expressed as the standardised thickness of an airway of inner perimeter 10 mm (Pi10).
Along many bedding surfaces adjoining the fracture, goethite-rich interlayers and pockets were formed, which is illustrated by sample Pi10 (Fig.