GFRA1(redirected from PI-linked cell-surface accessory protein)
GFRA1A gene on chromosome 10q26.11, that encodes a glial cell line-derived neurotrophic factor, which is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and neurturin, and mediates activation of the RET tyrosine kinase receptor.
GFRA1 mutations have been tentatively linked to Hirschsprung disease.
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