SERPINB5(redirected from PI-5)
SERPINB5A gene on chromosome 18q21.3 that encodes a member of the serine protease inhibitor (serpin) family that acts as a tumour suppressor by blocking the growth, invasion and metastatic properties of mammary tumours. SERPINB5 does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins; it has no serine protease inhibitory activity.
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