SERPINB5

(redirected from PI-5)

SERPINB5

A gene on chromosome 18q21.3 that encodes a member of the serine protease inhibitor (serpin) family that acts as a tumour suppressor by blocking the growth, invasion and metastatic properties of mammary tumours. SERPINB5 does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins; it has no serine protease inhibitory activity.
Mentioned in ?
References in periodicals archive ?
In comparison, PI-5 and PI-6 were synthesized using the diamine mixtures of 1,3,4-APB and 3,4'-ODA with different mole ratios (50:50 and 100:0), respectively.
The crystal phase was also observed in PI-3, PI-5, PI-6, and PI-7, and PI-4, similar to PI-2, was amorphous.
It was found that PI-6 without 3,4'-ODA has the lowest [T.sub.g] (255[degrees]C) and PI-5 using 1,3,4-APB/3,4'-ODA of 50/50 showed the highest one (282[degrees]C).
The polyimide derived from BPDA and a mixture of aromatic diamines with the molar ratio of 1,3,4-APB/3,4'-ODA = 50:50 (PI-5) showed lower melt viscosity than those derived from a mixture of 1,3,4-APB and 3,4'-ODA with molar ratios of 75:25 and 100:0, respectively.