O3FAR1

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O3FAR1

A gene on chromosome 10q23.33 that encodes a member of the rhodopsin family of G protein-coupled receptors that is a receptor for medium- and long-chain free fatty acids. O3FAR1 mediates a robust anti-inflammatory response, especially in macrophages and fat cells, by inhibiting TAK1 through a beta-arrestin 2 (ARRB2/TAB1)-dependent effect but independent of the G(q)/G(11)-coupled pathway. O3FAR1 mediates potent insulin-sensitising and antidiabetic effects by repressing macrophage-induced tissue inflammation.
References in periodicals archive ?
The sublime Kudos system from previous title PGR4 has been replaced by a Fans Rating.
Blur might not quite match PGR4 for thrills but it's an excellent game with more than enough content to keep players racing in the fast lane.
PGR4 is compatible with the Xbox 360 Wireless Racing Wheel and allows players to build a global racing community on Xbox live.
Competition is red-hot in the games racing market - with the likes of PGR4 and Sega Rally setting the standard.
If you got that addicted to Gran Tourismo, you'd spend an entire Saturday whiling away the hours - modifying cars with the curtains closed and drinking beer in your underpants - PGR4 will probably not appeal to you.
PGR4 has a huge selection of cars and bikes which can all be chosen to prove your superiority among your racing peers.
XBOX 360, the Tour Title Sponsor, will have the highly anticipated Halo 3, Forza Motorsport 2, Guitar Hero III: Legends of Rock and the new PGR4.
fter all, you'd think that titles such as Forza 2, Gran Turismo, PGR4 and Burnout Paradise would have all the bases covered.
After enjoying solid handling in PGR4 and Gran Turismo 5: Prologue in recent months, Grid gave me a shock.
This deep, meaningful debate was in reference to PGR4 which, for the first time for this franchise, pits the two types of machines against each other.