properdin

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properdin

 [pro´per-din]
a protein of the alternative complement pathway, augmenting complement activation. Called also factor P.

pro·per·din

(prō'per-din),
A control protein for the alternate complement cascade, properdin stabilizes the C3 convertase enzyme, a deficiency of which increases susceptibility to systemic meningococcal infections and can be inherited in an x-linked pattern.
See also: properdin system, component of complement, factor P.
[pro- + L. perdo, to destroy]

properdin

/pro·per·din/ (pro´per-din) factor P; a nonimmunoglobulin gamma globulin component of the alternative pathway of complement activation.

properdin

(prō-pûr′dn)
n.
A protein in blood serum that is a component of the innate immune system, acting as a positive regulator of the alternative pathway of the complement system.

pro·per·din

(prō'pĕr-din)
A group of proteins involved in resistance to infection that participate, in conjunction with other factors, in an alternate pathway to the activation of the terminal components of complement.
See also: properdin system, component of complement
[pro- + L. perdo, to destroy]

properdin

a normal, relatively heat-labile, nonantibody serum protein (a euglobulin) that, in the presence of complement component C3 and magnesium ions, is involved in the alternative complement pathway, and acts nonspecifically against gram-negative bacteria and viruses and plays a role in lysis of erythrocytes. It may act in conjunction with complement-fixing antibody.

properdin pathway
alternative complement pathway.