PEX10

PEX10

A gene on chromosome 1p36.32 that encodes peroxin-10, a protein involved in importing peroxisomal matrix proteins and which localises to the peroxisomal membrane. 
 
Molecular pathology
PEX10 mutations cause peroxisome biogenesis spectrum disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome.
References in periodicals archive ?
the homology search by screening the expressed sequence tag database using yeast PEX genes, successfully made it feasible to isolate human orthologue genes responsible for PBDs: (22), (24), (34) PEX1, (55), (56) PEX3, (57) PEX5, (58) PEX6, (59) PEX7, (60)-(62) PEX10, (63),(64) PEX12, (65) PEX13, (66) PEX14, (67) and PEX16.
1998) Mutation in PEX10 is the cause of Zellweger peroxisome deficiency syndrome of complementation group B.
1998) Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders.