PET scanning

PET scanning

Positron emission tomography. This is a diagnostic imaging technique based on the detection of gamma rays produced by the annihilation of positively charged electrons (positrons) emitted by specially prepared radioactive substances that have been injected intravenously. Substances labelled with oxygen-15, fluorine-18, carbon-11 or nitrogen-13 are most commonly used. PET scanning provides uniquely valuable images of tissues showing local metabolic activity, especially in the brain, the rate of glucose and oxygen consumption at various sites, blood flow, neurotransmitter activity and the fate of drugs. Positron-emitting substances have a very short half-life and must be prepared on site in a cyclotron. This limits the application of the technique.
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The PET scanning agent used in the study, [18F]flutemetamol (Vizamyl), binds with high affinity to beta-amyloid but rapidly clears from normal brain tissue; it was approved in October 2013 for PET imaging of the brain in adults being evaluated for Alzheimer's disease and dementia.
The use of baseline FDG-PET in lymphoma has been reported to change the stage and, hence, its treatment in approximately 10-20% of the patients.10,11 Hutchings et al showed that the treatment changed as a result of PET scanning in 9% of 99 prospectively recruited patients, and in 17% of patients who underwent integrated PET/CT, resulting in an upstaging and intensification of therapy.12
NHS Wales Shared Services Partnership, hosted by Velindre NHS Trust, may advertise a tender opportunity on behalf of Betsi Cadwaladr University Health Board (BCUHB) between April 2013 - March 2014 for a Mobile PET Scanning Service.BCUHB is currently compiling a business case to repatriate the PET Scanning of its patients from Christies Hospital to North Wales in the form of a mobile PET scanning service provided by a 3rd party.This Prior Information Notice is published to invite potential suppliers of such a service to make contact with the Health Board via its Procurement Lead, Joanne Liddle, to register their interest.
Positron Emission Tomography, or PET scanning, is rapidly emerging as one of the most useful forms of diagnostic imaging, especia with regard to diagnosing and managing cancer.
With respect to the inclusion of PET scanning in the initial evaluation of small cell lung cancer, the updated guidelines recommend that it be considered as a supplement to other studies, based on findings from a recent trial that showed it to be more accurate than conventional imaging for disease staging (Am.
For patients already diagnosed with cancer, PET scanning can help to establish the spread of tumours, aiding treatment planning.
A main focus of the centers will be to develop technologies such as three-dimensional protein imaging, which could be used to predict the function of the variations; whole-mouse imaging using PET scanning, which could more quickly detect tumor formation; microarray gene expression analysis; proteomics; and a whole new suite of bioinformatics tools to integrate the emerging data.
With the help of PET scanning, a noninvasive technology that can track chemical reactions in the brain, researchers in Switzerland found that people with MS fatigue exhibited impaired glucose metabolism in key brain areas where myelin loss appeared to have occurred.
STOCKHOLM -- Appropriate use of PET scanning provides useful diagnostic information in the evaluation of dementia, Dr.
TORONTO -- PET scanning can be used to select patients with recurrent colorectal cancer for whom resection surgery would be curative.
Sheng Pin Changlai, a visiting physician in the UCLA department of nuclear medicine, explained that current Medicare regulations require that a chest CT scan be done prior to PET scanning for staging of lung cancer.
The features were identified using a new radiolabeled tracer called [[[blank].sup.18]F]FDDNP in combination with PET scanning. The image was obtained by Dr.