phosphoenolpyruvate carboxylase(redirected from PEP carboxylase)
phosphoenolpyruvate carboxylaseAn enzyme that catalyses a two-step reaction: formation of carboxyphosphate and enolate form of pyruvate, and carboxylation of enolate with the release of phosphate. It replenishes oxaloacetate in the tricarboxylic acid cycle when operating in reverse. Phosphoenolpyruvate carboxylase is the recommended name for EC 220.127.116.11, orthophosphate:oxaloacetate carboxy-lyase (phosphorylating).
Phosphoenolpyruvate carboxylase has also been used for:
(1) Phosphoenolpyruvate carboxykinase (GTP), EC 18.104.22.168 (GTP:oxaloacetate carboxy-lyase (transphosphorylating));
(2) Phosphoenolpyruvate carboxykinase (pyrophosphate), EC 22.214.171.124 (pyrophosphate:oxaloacetate carboxy-lyase (transphosphorylating)); and
(3) Phosphoenolpyruvate carboxykinase (ATP), EC 126.96.36.199 (ATP:oxaloacetate carboxy-lyase (transphosphorylating)).