PEG-ADA
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adenosine
(a-den'o-sen?) [Ger. blend of adenine + ribose]A nucleotide containing adenine and ribose.
adenosine 3',5'-cyclic monophosphate
Abbreviation: AMPA cyclic form of adenosine. Its synthesis from adenosine triphosphate (ATP) is stimulated by an enzyme, adenylate cyclase (also called cyclic AMP synthetase). Adenosine 3',5'-cyclic monophosphate is important in a wide variety of metabolic responses to cell stimuli.
adenosine deaminase conjugated with polyethylene glycol
Abbreviation: PEG-ADAA cytoplasmic enzyme used to treat severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency. Trade name is Adagen.
See: severe combined immunodeficiency diseaseadenosine diphosphate
Abbreviation: ADPA compound of adenosine containing two phosphoric acid groups. ADP is used to synthesize ATP with the energy released in cell respiration. When ATP is used for cellular functions such as protein synthesis, ADP is reformed.
adenosine monophosphate
Abbreviation: AMP; 5'-AMPA substance formed by condensation of adenosine and phosphoric acid. It is one of the hydrolytic products of nucleic acids and is present in muscle, red blood cells, yeast, and other nuclear material.
Synonym: adenylic acidadenosine triphosphatase
Abbreviation: ATPaseAn enzyme that splits adenosine triphosphate to yield phosphate and energy.
adenosine triphosphate
Abbreviation: ATPA compound of adenosine containing three phosphoric acid groups. Its chemical formula is C10H16N5O13P3. ATP is present in all cells and is formed when energy is released from food molecules during cell respiration. Cells contain enzymes to hydrolyze ATP into ADP, phosphate, and energy, which is then available for cellular functions such as mitosis.
adenosine deaminase conjugated with polyethylene glycol
Abbreviation: PEG-ADAA cytoplasmic enzyme used to treat severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency. Trade name is Adagen.
See: severe combined immunodeficiency diseaseSee also: adenosine
Medical Dictionary, © 2009 Farlex and Partners
PEG-ADA
An orphan drug that is useful in treating SCID related to ADA deficiency.
Mentioned in: Severe Combined Immunodeficiency
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.