ETV4

(redirected from PEA3)
Also found in: Acronyms.

ETV4

A gene on 17q21 that encodes a transcription activator that binds to the adenovirus E1A gene enhancer, specifically at the core-binding sequence 5'[AC]GGA[AT]GT-3'.
References in periodicals archive ?
Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine kerainocytes stimulated with epidermal growth factor or phorbolester.
(2008) conducted deletion, bioinformatics, and transcription-factor binding studies on the distal segment of the 4.4-kb MMP-1 promoter, they found PEA3 transcription factors acting as robust repressors, with binding sites at a "tandem" position (--3838 and--3824 relative to transcriptional start site).
The Ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis.
y PEA3 con las respectivas de la gran empresa B (MEB1 y PEB1).
Dannenberg, "Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3," The Journal of Biological Chemistry, vol.