PDGFRA

(redirected from PDGFR-2)

PDGFRA

A gene on chromosome 4q12 that encodes a tyrosine-protein kinase which acts as a cell surface receptor for PDGFA, PDGFB and PDGFC, playing a key role in regulating embryonic development, survival and chemotaxis and, depending on context, up- or downregulates cell proliferation and migration.