Three isolates had serotypes included in
PCV7, whereas nine isolates did not.
Soon after introduction of
PCV7, serotype 9V IPD became rare (1,2), and 19A became the predominant representative of the ST156 lineage within ABCs (14,32).
9% reduction in antibiotic prescriptions for AOM was demonstrated from 1997 to 2004 following implementation of the
PCV7 immunisation programme.
However, after wide application of
PCV7, "serotype replacement", a phenomenon that
PCV7 serotypes decreased with concurrent increase of NVTs among invasive and noninvasive diseases was observed.
000) Las tasas de enfermedad en pacientes expuestos a vacunacion con
PCV7 podemos encontrarlas en la tabla 1.
However, the antibody responses and safety profile observed in this trial are similar to those observed in other trials comparing PCV13 with
PCV7 (10, 12-16).
2/100,000 between 1998 and 2007--most likely because routine use of the
PCV7 vaccine in children has resulted in decreased carriage and transmission of infection from children to adults.
PCV7 was introduced in the infant immunisation programme in the USA in 2000.
Before the introduction of
PCV7, regional variations in the prevalence of antibiotic resistance were considered to be caused by regional differences in antibiotic use, leading to differences in the intensity of selective pressure acting on the bacterial population (9).
2) suggested that the increasing trend in empyema was also present before
PCV7 introduction; for this reason, a direct association with the
PCV7 vaccination program is unlikely.
Children were classified into in 3 groups: i) those born in the period January 1, 1994 to April 30, 1997 and targeted by the 2002 mass campaign with PPSV23; ii) those born in the period May 1, 1997 to March 31, 2002 and targeted by the
PCV7 catch-up campaign initiated in the spring of 2002; and iii) those born in the period April 1, 2002 to December 31, 2005 and targeted by the
PCV7 routine infant program.
When the levels of immunity were measured against multiple childhood illnesses, the researchers found that the children who had received the PCV13 had no less or weaker immune response than the children who had received the
PCV7.
