PCSK5

PCSK5

A gene on chromosome 9q21.3 that encodes a broadly active endoprotease of the peptidase S8 family involved in the constitutive and regulated secretory pathway. It cleaves the RX(K/R)R consensus motif and plays an essential role in establishing pregnancy through the proteolytic activation of key factors, such as BMP2 and CALD1.
References in periodicals archive ?
049 transporter activity Group GOID Gene symbol or representative public ID Signal GO:0005030 NTRK1, NTRK2 transduction GO:0001614 P2RX4, P2RY2, ENSGALG00000012080 GO:0016502 P2RX4, P2RY2, ENSGALG00000012080 GO:0043121 NTRK1, NTRK2 GO:0035586 P2RX4, P2RY2, ENSGALG00000012080 GO:0004888 OXTR, LOC431251, SSTR3, CHRM2, ADRA2B, P2RX4, P2RY2, EDNRB2, GABRB2, GABRG2, LOC428961, NPFFR2, GRIN2B, GRIN3A, NTRK1, NTRK2, EPHB6, DDR2, TMPRSS6, PCSK5, CCKAR, IFNAR2, CSF1R, TLR5, OR10A7, LOC768958, LOC769317, LOC777484, GPR39, GPR97, ENSGALG00000017405, ENSGALG00000017093, ENSGALG00000012080.