PCDHA4 | definition of PCDHA4 by Medical dictionary
PCDHA4 A gene on chromosome 5q31 that encodes a putative calcium-dependent cell-adhesion protein, which may be involved in establishing and maintaining specific neuronal connections in the brain.
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References in periodicals archive
In an independent cohort test, the methylated PCDHA4
and PCDHA13 test is equally sensitive but more specific than the human papillomavirus (HPV) test in the diagnosis of [CIN2.sup.+] .
More than 20 genes, including CADM1/MAL, PAX1, SOX1, ZNF582, PCDHA4
, and PCDHA13, have been confirmed to be associated with the lesions of CIN2 and greater.
Gene Product Otoa NM_139310 Otoancorin Cabp2 NM_013878 Calcium binding protein 2 Sod3 NM_011435 Superoxide dismutase 3 Hspb8 NM_030704 Heat shock protein 8 Hsf5 NM_001045527 Heat shock transcription factor member 5 Otof NM_031875 Otoferlin Calca NM_007587 Calcitonin/calcitonin-related polypeptide alpha Pcdha4
NM_007766 Protocadherin alpha 4 Gene Symbol Fold Change p-Value Otoa +3.4 0.04 Cabp2 +1.6 0.003 Sod3 +2.0 0.03 Hspb8 +1.3 0.02 Hsf5 +1.8 0.02 Otof -1.8 0.04 Calca -1.9 0.04 Pcdha4
-1.3 0.001 Table 2.