CDH3

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CDH3

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH3 is also a retired HUGO symbol for what is now designated CDH15, see there.

Molecular pathology
Loss of heterozygosity mutations of CDH3 occur in breast and prostate cancer; aberrant expression of cadherin 3 occurs in cervical adenocarcinomas. CDH3 mutation causes congenital hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia with ectrodactyly and macular dystrophy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The abovementioned cognitive technologies would form the basis of pCAD (Figure 1, A through D) and would enable extensive integration of heterogeneous data sources, including laboratory information system (LIS), enterprise information system, and picture archiving and communication system data.
We conducted a case-control study of 560 patients with newly diagnosed angiographically documented PCAD and an equal number of control patients with normal coronary arteries (no luminal stenosis at coronary angiography; Gensini score = 0).
(ii) banks that were undercapitalized on the basis of regulatory capital ratios from the PCAD database or the report disposition dates of exams for which banks are rated CAMELS 5.
The study may be the first to assess premature coronary artery disease (PCAD) in a predominantly nonwhite population, Dr.
Release 8.7 also includes support for Altium's PCAD 2004 and the next product update of Mentor's PADS PCB layout software, as well as a number of other software fixes.
Before joining Quickturn, he was the EDA marketing manager for PCAD products for seven years.
PCB, IC, Schematic formats supported include: Cadence Allegro, Concept, CIF, Design Architect, GDS-II, Gerber, Mentor Board Station, Orcad, PADS, PCAD, Protel, Zuken.
PCB, IC and schematic formats supported include: Cadence Allegro, Mentor Board Station, Design Architect, Zuken CADSTAR, PADS, Orcad, PCAD, GDS-II, CIF, Gerber, GenCAM and others.
Format support has been added for Mentor Board Station and Design Architect, Cadence Allegro, Allegro Extract, PADS Power PCB, Zuken CADSTAR, PCAD 2002 and others.