IFRD1

(redirected from PC4)
Also found in: Acronyms.

IFRD1

A gene on chromosome 7q31.1 that encodes an IFN-gamma-related protein, which may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration.

Molecular pathology
IFRD1 mutations are associated with sensory/motor neuropathy with ataxia; it may also be involved in modulating the pathogenesis of cystic fibrosis lung disease.
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References in periodicals archive ?
The PC9 and PC4 outwardly resembled a Ruger 10/22, with the barrel breech end inserted into an angular receiver block and a black polymer stock wearing the seemingly obligatory trademark Ruger carbine band.
Figure 8 illustrates the time-varying prestress loss of beams PC1 and PC4, monitored using EM sensors, where the development of prestress loss with time is similar in pattern to concrete creep and shrinkage.
The major loadings in PC4 were DOC and cropping intensity, and the different signs showed that this PC was related to the decline in DOC as cropping intensity increased.
The PC false colour image (RGB) (Figure 6(f)) was obtained by coding the PC3, PC4, and PC5 score values as the intensity of the red, green, and blue channels.
The leading IC1 reaches values of +5 standard deviations in the years 1983 and 1997 of strong El Ninos, during which PC1, PC3, PC4, and PC11 are synchronised (see also Figures 5(a) and 5(b) and Table 5).
In detail, PC1 explains 49% of the total variance contained in the data, whereas PC2, PC3, and PC4 explain 19, 11, and 4% of the total variance, respectively.
Variance proportions explained by PC1, PC2, PC3, and PC4 were found as 71.84%, 16.58%, 6.34%, and 5.04%, respectively.
PCA transform was implemented on the ASTER TIR bands (10, 11, 12, 13, and 14) to generate five different principal components (PC1, PC2, PC3, PC4, and PC5).
PC4 was stimulated by delicately twisting the needles according to the standard reinforcement technique for 2 minutes or until a sensation of moderate "de qi" (feeling of soreness, numbness, distension, or pain) was achieved.