PCSK1

(redirected from PC1)
Also found in: Acronyms.

PCSK1

A gene on chromosome 5q15-q21 that encodes a peptidase S8 family convertase involved in processing pairs of basic amino acid residues located on prohormones and other protein precursors (e.g., POMC, renin, enkephalin, dynorphin, somatostatin and insulin).

Molecular pathology
Defects in PCSK1 cause proprotein convertase 1 deficiency.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The biplot for the wheat FHB data explained 77% (46 and 31% by PC1 and PC2, respectively) of the total variation (Fig.
PC1 Robinson volunteered for a six-month Individual Augmentee (IA) assignment with Joint Task Force Guantanamo Bay, Cuba, where he provided service to 3,500 Sailors, Soldiers, and civilian personnel in support of the war on terror.
It can be used to identify superior cultivars and test environments that facilitate identification of such cultivars, provided that the target mega-environment is sufficiently sampled and that the genotype PC1 scores have near-perfect correlation (say, r [is greater than] 0.95) with the genotype main effects.
In all years, the location PC1 scores were of the same sign or near zero (results not shown).
For a specific genotype at a specific location, the location-centered yield is approximated by the product of the genotypic PC1 score by the location PC1 score, plus the product of the genotypic PC2 score by the location PC2 score.
Provincial Minister expressed indignation over delays in approval and submission of PC1 regarding development projects for Gawadar pledged full support for honest and diligent officers of C and W department.
In pursuance of the said orders, once again a second revised PC1 was prepared by Wapda.
Later he issued directions to Secretary Live Stock Aijaz Ahmed Mehsar to complete all necessary formalities regarding PC1 within a week to build cattle colony without further delay.
There was no respite and Hunt reached PC1 (140km) in front of both Rajhi and Joan Roma, with Matthieu Serradori in fourth place.
There was no respite and Hunt reached PC1 (140km) in front of both al-Rajhi and Joan Roma, with Matthieu Serradori in fourth place.
The original PC1 cost of this project is Rs938 million.
The first three principal components explained 81.38% of the total variation in the data: principal component 1 (PC1), PC2 and PC3 explained 38.66%, 25.02% and 17.70% of the data, respectively.