PCSK1

(redirected from PC1)
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PCSK1

A gene on chromosome 5q15-q21 that encodes a peptidase S8 family convertase involved in processing pairs of basic amino acid residues located on prohormones and other protein precursors (e.g., POMC, renin, enkephalin, dynorphin, somatostatin and insulin).

Molecular pathology
Defects in PCSK1 cause proprotein convertase 1 deficiency.
References in periodicals archive ?
We explore the nature of the relationship between connectedness and media visibility by including PC1 Squared.
Fourteen significant SNPs were associated with PC1 (six in genic regions, eight in intergenic regions), eleven SNPs were associated with PC2 (six in genic regions, five in intergenic regions), and two SNPs were associated with PC3 (one in a genic region, one in an intergenic region).
The Zenascope[TM] PC1, an ultraviolet-visible spectrometer that achieves quantitative optical spectroscopy in turbid media, uses standard spectroscopic measurement hardware, proprietary software, and patented algorithms to achieve rapid, quantitative, and non-destructive analysis of biological tissue characteristics (biomarkers) that reflect the underlying function and composition of biological tissue.
The SwitchServer can be used directly by logging onto PC1 locally or remotely.
As shown in Table 2, we were able to develop a domain interpretation of PC1 through PC4, (2) and we could relate that interpretation to the seven dimensions identified using CAC.
Principal component analysis and correlation coefficients analysis in durum wheat landraces facilitate Identify desirable traits and their relationship with yield and reliable classification of genotypes, According to the results in this study it is concluded that a good hybridization breeding program can be initiated by the selection of genotypes from the PC1 and PC2, identification of subset of core genotypes and correlated morphological characters with possible utility for specific breeding purposes.
b) x Axis is PC1 of albumin, DBP, CRP, B2M, and CysC glycation; y axis is PC1 of apoAI and apoCI oxidation; z axis is PC1 of native apoC-I, apoC-I [3-57], native RANTES, and RANTES [3-68].
The terms PC1 and PC4 turned out to be insignificant, and hence dropped to obtain the final regression equation for SSI as a function of PC2 and PC3:
From the low magnification micrographs, the dark ellipses or lines are organoclay in the PC1 blend (Fig.
PC1 explains the largest amount of variance in the data.
Learning on the job can be a stronger tool than just reading it out of a book," said PC1 (SW/AW) Keona Ellis, Leading Petty Officer for the IKE Post Office.
Positive scores for PC1 correlated with moist areas during July, October, and January and dry areas during May.