New data show that the herbal supplement PC SPES contained even more contamination than was recognized when the product was abruptly pulled from store shelves in early 2002.
A detailed analysis using gas chromatography and mass spectroscopy has shown that some lots of PC SPES marketed between 1996 and 2001 indeed contained varying levels of not only warfarin and DES, but also indomethacin.
The origin of the three potent synthetic drugs in PC SPES is puzzling," they said.
But by the summer of 2001, rumors of untoward effects and possible adulteration of PC SPES began circulating among prostate cancer patient groups.
Since the withdrawal of PC SPES, other manufacturers have begun marketing their own similar formulations, under names such as PC Care, PC Plus, and PC Calm.
, capsules containing a light brown powder marketed for ``prostate health,'' contains warfarin, a powerful blood thinner often sold under the brand name Coumadin, California health officials said.