Diagnostic utility of PAX8 and PAX2
immunohistochemistry in the identification of metastatic mullerian carcinoma in effusions.
6 Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P: Pax2
, a new murine paired-box-containing gene and its expression in the developing excretory system.
and PAX8 are expressed in both tumors, they do not help in the differential diagnosis (37,38).
Immunohistochemistry (IHC) showed positive cytokeratin (CK) 18, vimentin, PAX2
, PAX8, and focal CD10 staining [Figure 2]b, [Figure 2]c, [Figure 2]d and negative staining for CK 7, CK 20, CD56, synaptophysin, and chromogranin A.
and PAX8 expression in primary and metastatic Mullerian epithelial tumors: a comprehensive comparison.
("The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns") determine that Pax2
, Sox2, and Prox1 have differential and overlapping temporospatial expression patterns during the development of vestibular and auditory sensory organs in mice.
Uterine congenital anomalies have a heterogeneous genetic basis, with implications of Wilms tumour 1 gene (WT1), paired box gene 2 (Pax2
), WNT2, pre-B-cell leukemia transcription factor 1 (PBX1), and homeobox (HOX) genes .
The CAIX, PAX8, PAX2
, CD10, and RCC demonstrate restricted expression in CCRCC but not in angiosarcomas.
Rohr, "Zebrafish hhex, nk2.1a, and pax2
.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors," Developmental Biology, vol.
Within the neural epithelial-derived optic vesicle, animal studies have demonstrated that Pax6 acts together with additional transcription factors such as Pax2
, Six6, Gsx2, Pax5, and Lhx2 to regulate invagination to form the bilayered cup that will become the retina, retinal pigmented epithelium, and iris pigmented epithelium [8, 10, 12, 46].
The mRNA expression of WT-1, Pax2
, and Pax8 was downregulated by CsA treatment.
Role of Pax genes in eye evolution: a cnidarian PaxB gene uniting Pax2
and Pax6 functions.