GPR172A

(redirected from PAR1)
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GPR172A

A gene on chromosome 8q24.3 that encodes a riboflavin transporter, which also acts as a receptor for porcine endogenous retrovirus subgroup A (PERV-A).
References in periodicals archive ?
Before a traumatic event, PAR1s usually tell amygdala neurons to remain active and produce vivid emotions.
When PAR1 was switched off at the onset of sepsis, 60 percent the mice survived.
We wanted to optimize this mutant to completely abrogate activity toward fibrinogen and PAR1.
The data also provide initial characterization of receptor molecules that appear to be distinct from the PAR1 thrombin receptor.
Zontivity locks the PAR1 receptor into a conformation that prevents thrombin recognition, thereby halting platelet activation and thrombosis at this key step.