F2RL2

(redirected from PAR-3)

F2RL2

A gene on chromosome 5q13 that encodes a member of the protease-activated receptors (PARs), which belong to the G protein-coupled cell surface receptor family. F2RL2 is a co-factor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4, and plays an essential role in hemostasis and thrombosis.
References in periodicals archive ?
At the mountainous par-5 fourteenth and fifteenth, he completed a tremendous treble with a 2 at the 235-yard sixteenth - the longest par-3 on the course.
Okello started off the round with a triple-bogey at the par-5, first before making amends with birdies at the par-3, third and the par-5, fifth.
Sharing about 28% sequence homology with human PAR-1 and PAR-2, human PAR-3 is activated in a very similar fashion to human PAR-1 with a thrombin cleavage site within the extracellular amino terminus [LPIK.sup.38] [down arrow] [T.sup.39]FRGAP [15].
The 245-yard, par-3 fifth hole is actually longer than the 242-yard, par-4 third and the 233-yard, par-4 sixth.
Both bogeyed the par-3 11th hole and parred the par-4 12th hole, although Peterson's birdie bid at the 12th was close.
Following pars at the seventh and eighth, hit the jackpot with a superb birdie at the long 218-yard par-3 ninth, and turned in a 2-under par 33.
On the first nine, Snow impressed to record a total of 32 having played bogey-free, and picking up birdies on the par-3, fourth, the par-5, sixth and the par-4, ninth.
He kept on course with two pars, before hitting the jackpot at the 165-yard par-3 seventh, recording his second birdie 2, then hit the heights, completing a hat-trick of birdies at the 289-yard par-4 eighth, and the 516-yard par-5 ninth to turn in a 4-under par 32.
Madoya birdied the Par-3, second and par-5 sixth before bogeying at the par-4, third and par-3 fourth in the first nine.
He rifled his teeshots on the first three holes and, with majestic short iron work plus red-hot putting, produced his subpar scores and perfectly found the green at the 195-yard par-3 for his fourth successive birdie, and followed with a steady par at the long fifth before lighting the touch paper, and rejoining the birdie trail at the par-4 sixth and second short-hole birdie at the 170-yard seventh.
On the first nine, he dropped shots at the Par-3 second and the Par-5 fourth but recovered with a birdie on the Par-4 sixth for a total of 37 having held par on the rest of the holes.
Following a par at the 213-yard par-3 twelfth, the alarm bells rang again, as he slumped on all fours with another bogey at the 444-yard par-4 thirteenth.