PAPA syndrome


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Related to PAPA syndrome: SAPHO syndrome

PAPA syndrome

(pah'pah sin'drōm),
An autosomal dominant syndrome consisting of pyogenic sterile arthritis, pyoderma gangrenosum, and acne.
A rare autosomal dominant [MIM 64416] condition characterised by the acronym PAPA:
pyogenic arthritis
pyoderma gangrenosum and
cystic acne
Lab Hypogammaglobulinaemia, elevated tumour necrosis factor-alpha
Management Intra-articular corticosteroid therapy, methotrexate, colchicine