PANK1

PANK1

A gene on chromosome 10q23.31 that encodes a member of the pantothenate kinase family, which are key enzymes in coenzyme A (CoA) synthesis. PANK1 catalyses the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition.
References in periodicals archive ?
PANK1 (pantothenate kinase-1) influences the level of intracellular CoA (coenzyme A) by catalyzing the rate limiting step in the CoA synthesis pathway [126].