P2RY2

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P2RY2

A gene on chromosome 11q13.5-q14.1 that encodes a subfamily of G protein-coupled receptors, which acts as a receptor for adenosine and uridine nucleotides and may participate in controlling the cell cycle of endometrial carcinoma cells.

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Silencing P2Y2R expression inhibited ATP-induced human HCC cell proliferation and migration, and, in nude mice that were implanted with human HCC cells, blocking P2Y2R inhibited cell growth [178].

Ion Channels and Oxidative Stress as a Potential Link for the Diagnosis or Treatment of Liver Diseases

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