P2RY1(redirected from P2Y purinoceptor 1)
P2RY1A gene on chromosome 3q25.2 that encodes a G protein-coupled receptor that acts as a receptor for extracellular ATP and ADP. In platelets, P2RY1 binding to ADP leads to mobilisation of intracellular calcium ions by activating phospholipase C, a change in platelet shape and platelet aggregation.
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