PRPF8

(redirected from P220)
Also found in: Acronyms.

PRPF8

A gene on chromosome 17p13.3 that encodes protein which is a central component of the spliceosome and thought to play a role in aligning pre-mRNA 5'- and 3'-exons for ligation. It interacts with U5 snRNP proteins SNRP116 and WDR57/SPF38, and with EFTUD2 and SNRNP200.

Molecular pathology
Defects in PRPF8 cause retinitis pigmentosa type 13.
References in periodicals archive ?
The P226 (in fact the entire P220 series) are renowned for their accuracy, no doubt a result of the precision with which they are made.
The Sig P220 SAO Match is extremely accurate for a factory produced .
He said three fourths of the original proposed P220 billion is enough to help the agency improve the agriculture sector.
The domestic PSC worth P220 will eventually increase to P300 by January 1.
Since both special pistols cost as much to make as a standard, "bullet-shooting" P220, P226, or P229, their prices will be about the same as their fully functional equivalents.
The company initially shipped extra P220 pistol magazines to the Louisiana State Police, then, at the agency's request, sent all available remaining P220 magazines.
The Sig P220 was first introduced in 1976 and while there has been a wide range of different calibers chambered for this great pistol, the .
Citing DA's Agribusiness and Marketing Assistance Service (AMAS) price monitoring, DA Secretary Proceso Alcala said price of garlic per kilo at the Mandaluyong Public Market was down to P140 last July 23, cheaper by P80 from the P220 per kilo last July 11.
In January 2006, SIGARMS introduced the SAO (Single Action Only) variation of their P220 .
Available models are the P220, P225, P226, P228, P229, P232, P239, SP2340 and SP2009 in calibers .
The Sig-Sauer P220 is significant in that it is the first of the double-action line of auto pistols that feature a decocking mechanism that dispenses with the need for a manual safety.
4 million in 2016, registering a P220,000 increase.