p-aminobenzoic acid


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p-aminobenzoic acid

 (PAB) (PABA) [ah-me″no-ben-zo´ik]
a substance required for the synthesis of folic acid by many organisms; it is included in the B vitamin complex, although it is not an essential nutrient for humans. It is synthesized by many bacteria; sulfonamides act by blocking its synthesis; it also absorbs ultraviolet light, specifically UVB rays, and is used as aminobenzoic acid as a topical sunscreen.

p-a·mi·no·ben·zo·ic ac·id (PABA),

(ă-mē'nō-ben-zō'ik as'id),
4-aminobenzoic acid, a factor in the vitamin B complex, required for biosynthesis of folate; neutralizes the bacteriostatic effects of the sulfonamides because it furnishes an essential growth factor for bacteria; elevated concentrations of the sulfonamides interfere with use of this agent and of folates; used as an ultraviolet screen in lotions and creams. It is produced in a test of pancreatic function.

p-ami·no·ben·zo·ic acid

(PABA) (ă-mē'nō-ben-zō'ik as'id)
A factor in the vitamin B complex, a part of all folic acids and required for its formation; neutralizes the bacteriostatic effects of the sulfonamides because it furnishes an essential growth factor for bacteria, with the use of which sulfonamides interfere; used as an ultraviolet screen in lotions and creams.
References in periodicals archive ?
Fischer, "Ion-Pair RP-HPLC Determination of Sugars, Aminosugars and Uronic Acids after Derivatization with p-Aminobenzoic Acid," Anal.
Esters of p-aminobenzoic acid (PABA), a class of analgesics are prepared by Fischer Esterification, a method, commonly employed for the synthesis of esters.
These compounds have similar chemical structures, consisting of a reduced pteridine moiety coupled through a methylene group to p-aminobenzoic acid (pABA) [4], to which glutamic acid is attached via an amide bond.
Esterification of p-aminobenzoic acid was done by Fischer esterification method [27].
Results for BIO are expressed as enzyme response units (ERU), where 1 ERU = 1 [micro]mol/dL p-aminobenzoic acid produced over the course of 90 min from the biotin-p-aminobenzoic acid substrate.