Oxygen free radicals

Oxygen free radicals

Reactive molecules containing oxygen and can cause cell damage.
Mentioned in: Insecticide Poisoning
References in periodicals archive ?
To explore this idea further, the researchers tested the strength of the flies antioxidant defenses against toxic versions of several chemicals found in cells called oxygen free radicals.
Oxygen free radicals impair both the cellular membrane and intracellular structures.
Emblica is unique in that it can neutralize both nitrogen and oxygen free radicals.
The levels of inflammatory molecules, oxygen free radicals and expression of genes which are among the makers of cellular ageing dropped to the level that would be expected in younger cells.
Macrophages are activated when there is infection or inflammation, with toll-like receptors releasing NO or oxygen free radicals that may damage the tissue.
Oxygen free radicals have been reported to play an important role in the pathogenesis of a number of cardiovascular diseases (CVDs) such as atherosclerosis, ischemia, hypertension, cardiomyopathy, cardiac hypertrophy and congestive heart failure by both in vivo and in vitro studies [31-35].
This then led to less efficient energy production and more release of oxygen free radicals, toxic by-products of mitochondrial metabolism.
On closer examination, the researchers found that resveratrol mitigated the damage done by oxygen free radicals, generated by the breakdown of the dopamine, and activated protein signalling pathways that appeared to promote cell survival.
Normally, oxygen free radicals are neutralized by natural antioxidants such as vitamin E, or enzymes such as superoxide dismutase (SOD).
Again, the TLR4-deficient mice produced fewer oxygen free radicals in response to polluted air than did normal mice.
Tschemia exerts multiple insults in microcirculation frequently accompanied by endothelial cell injury, enhanced adhesion of leukocytes, macromolecules efflux, production of oxygen free radicals and mast cell degran-ulation3.
Oxygen may increase lung injury by providing oxygen free radicals.